HANDLS Biology publications

1. Chitrala KN, Hernandez DG, Nalls MA, Mode NA, Zonderman AB, Ezike N, Evans MK. Race-specific alterations in dna methylation among middle-aged african americans and whites with metabolic syndrome. Epigenetics. 2019. doi:10.1080/15592294.2019.1695340.

2. Tajuddin SM, Hernandez DG, Chen BH, Noren Hooten N, Mode NA, Nalls MA, Singleton AB, Ejiogu N, Chitrala KN, Zonderman AB, Evans MK. Novel age-associated dna methylation changes and epigenetic age acceleration in middle-aged african americans and whites. Clinical Epigenetics. 2019;11(1):119. doi:10.1186/s13148-019-0722-1.

3. Prince CS, Noren Hooten N, Mode NA, Zhang Y, Ejiogu N, Becker KG, Zonderman AB, Evans MK. Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome. Aging (Albany NY). 2019. doi:10.18632/aging.102135.

4. Dluzen DF, Noren Hooten N, De S, Wood W. H., Zhang Y, Becker KG, Zonderman AB, Tanaka T, Ferrucci L, Evans MK. Extracellular rna profiles with human age. Aging Cell. 2018;17(4):e12785. doi:10.1111/acel.12785.

5. Freeman DW, Noren Hooten N, Eitan E, Green J, Mode NA, Bodogai M, Zhang Y, Lehrmann E, Zonderman AB, Biragyn A, Egan J, Becker KG, Mattson MP, Ejiogu N, Evans MK. Altered extracellular vesicle concentration, cargo and function in diabetes mellitus. Diabetes. 2018;67(11):2377-2388. doi:10.2337/db17-1308.

6. Eitan E, Green J, Bodogai M, Mode NA, Baek R, Jorgensen MM, Freeman DW, Witwer KW, Zonderman AB, Biragyn A, Mattson MP, Noren Hooten N, Evans MK. Age-related changes in plasma extracellular vesicle characteristics and internalization by leukocytes. Scientific Reports. 2017;7(1):1342. doi:10.1038/s41598-017-01386-z.

7. Dluzen DF, Noren Hooten N, Zhang Y, Kim Y, Glover FE, Tajuddin SM, Jacob KD, Zonderman AB, Evans MK. Racial differences in microRNA and gene expression in hypertensive women. Science Reports. 2016;6:35815. doi:10.1038/srep35815.

8. Noren Hooten N, Martin-Montalvo A, Dluzen DF, Zhang Y, Bernier M, Zonderman AB, Becker KG, Gorospe M, de Cabo R, Evans MK. Metformin-mediated increase in dicer1 regulates microRNA expression and cellular senescence. Aging Cell. 2016;15(3):572-581. doi:10.1111/acel.12469.

9. Noren Hooten N, Ejiogu N, Zonderman AB, Evans MK. Protective effects of bdnf against c-reactive protein-induced inflammation in women. Mediators of Inflammation. 2015;2015:516783. doi:10.1155/2015/516783.

10. Noren Hooten N, Fitzpatrick M, Wood W. H., De S, Ejiogu N, Zhang Y, Mattison JA, Becker KG, Zonderman AB, Evans MK. Age-related changes in microRNA levels in serum. Aging. 2013;5(10):725-740. http://www.ncbi.nlm.nih.gov/pubmed/24088671.

11. Noren Hooten N, Ejiogu N, Zonderman AB, Evans MK. Association of oxidative dna damage and c-reactive protein in women at risk for cardiovascular disease. Arterioscler Thromb Vasc Biol. 2012;32(11):2776-2784. doi:10.1161/ATVBAHA.112.300276.

12. Bhatnagar P, Lu X, Evans MK, Laveist TA, Zonderman AB, Carter DL, Arking DE, Fletcher CA. Genetic variants in platelet factor 4 modulate inflammatory and platelet activation biomarkers. Circulation Cardiovascular genetics. 2012;5(4):412-421. doi:10.1161/CIRCGENETICS.111.961813.

13. Trzeciak AR, Mohanty JG, Jacob KD, Barnes J, Ejiogu N, Lohani A, Zonderman AB, Rifkind JM, Evans MK. Oxidative damage to dna and single strand break repair capacity: Relationship to other measures of oxidative stress in a population cohort. Mutation Research. 2012;736(1-2):93-103. doi:10.1016/j.mrfmmm.2012.01.002.

14. Noren Hooten N, Abdelmohsen K, Gorospe M, Ejiogu N, Zonderman AB, Evans MK. MicroRNA expression patterns reveal differential expression of target genes with age. PLoS One. 2010;5(5):e10724. doi:10.1371/journal.pone.0010724.

15. Trzeciak AR, Barnes J, Ejiogu N, Foster K, Brant LJ, Zonderman AB, Evans MK. Age, sex, and race influence single-strand break repair capacity in a human population. Free Radical Biology & Medicine. 2008;45(12):1631-1641. doi:10.1016/j.freeradbiomed.2008.08.031.

16. Hooten NN, Evans MK. Age and poverty status alter the coding and noncoding transcriptome. Aging. 2019;11(4):1189-1203. doi:10.18632/aging.101823.

17. DeMarino C, Pleet ML, Cowen M, Barclay RA, Akpamagbo Y, Erickson J, Ndembi N, Charurat M, Jumare J, Bwala S, Alabi P, Hogan M, Gupta A, Hooten NN, Evans MK, Lepene B, Zhou W, Caputi M, Romerio F, Royal W, El-Hage N, Liotta LA, Kashanchi F. Antiretroviral drugs alter the content of extracellular vesicles from hiv-1-infected cells. Scientific reports. 2018;8(1):7653. doi:10.1038/s41598-018-25943-2.