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Neighborhood socioeconomic status is associated with cardiovascular disease prevalence and risk factors in an African American cohort

Mitchell CD, Waldstein SR, Kelley-Moore J, Evans MK, Zonderman AB. Neighborhood socioeconomic status is associated with cardiovascular disease prevalence and risk factors in an African American cohort. Paper presented at the 65th Annual Meeting of the American Psychosomatic Society; 7-10 March 2007; Budapest, Hungary. Annals of Behavioral Medicine. 2007;33:S31.

Meritorious Student Paper. Using the 2000 Census and data collected from 639 African American participants (ages 30-64; 44% male) in an ongoing NIA Intramural area probability study called “Healthy Aging in Neighborhoods of Diversity across the Life Span” (HANDLS), we examined how self-reported cardiovascular disease (CVD) prevalence and risk factors differ across four predominantly African American neighborhoods in Baltimore, MD. Two relatively high SES neighborhoods and two relatively low SES neighborhoods comprised the sampling frame. After adjusting for age, gender, education, body mass index (BMI) and smoking status, there was a higher prevalence of self-reported CVD among African Americans in the low SES neighborhoods compared to high SES neighborhoods (Odds Ratio [OR] = 2.11, 95% confidence interval [CI]: 1.04, 4.29). African Americans living in low SES neighborhoods were more likely to smoke (OR = 1.96, 95% CI: 1.39, 2.78). After controlling for demographics, BMI, self-reported CVD/stroke, and smoking status, standing systolic (p = 0.018) and diastolic (p < 0.001) blood pressure as well as seated diastolic blood pressure (p = 0.047) and apical pulse (p < 0.001) were higher for residents of low SES neighborhoods. Residents of low SES neighborhoods also displayed a trend toward seated diastolic blood pressure in the hypertensive range relative to those in high SES neighborhoods (p = 0.063). In sum, living in a low SES neighborhood was significantly associated with CVD risk factors, independent of several individual-level characteristics such as education, BMI, and smoking status. This study suggests that neighborhood socioeconomic context may contribute to variation in CVD risk observed among African Americans.




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